Vitamin C

On Oxidative Stress, Electrons and the "Dosage Lie"

• “Once something gets etched into the pages of the medical textbook, and medical school professors throughout the country teach it to medical students and doctors in post-graduate training, any contradictions to this orthodox body of knowledge get summarily ignored once these impressionable trainees become practicing physicians.” – Dr. Thomas Levy

• “At the height of the polio epidemic in 1949, when all young parents lived in fear that their babies and young children would be the next victims, Frederick R. Klenner, M.D., published that he had successfully cured 60 out of 60 polio patients who had presented in his office or to the emergency room. Furthermore, he reported that none of the 60 patients treated had any residual damage from the polio virus that often left its survivors crippled for life. This evidence was subsequently presented by Klenner in 1949 to an annual session of the American Medical Association that dealt with the treatment of polio patients.” – Dr. Thomas Levy

My Vitamin C story started when earlier this year Amelia wrote to me saying:

What else have they lied to me about? The biggest lies are the hardest to come to terms with: how could they lie to so many people about something so important for so long? I’d say that a contender for their biggest lie is they have never told you there is a safe, cheap, effective, universal antibiotic, antiviral, antitoxin: vitamin C. (Would you take any vaccine if you knew you could be quickly, safely cured if you caught the disease? Would you go to the doctor for a prescription of antibiotics for a minor bacterial infection if you could safely self-medicate with vitamin C from the supermarket?)

Most animals make vitamin C and increase the amount they make when they have an infection. Humans, other apes and guinea pigs all lost the ability to make vitamin C so have to consume it. For 60 - 70 years, doctors have understood that using high doses of vitamin C, usually through intravenous injections, they can cure viral and bacterial infections and cure people who have been poisoned by snakes, spiders, industrial chemicals, legal and illegal drugs.

Have a look at Dr Levy's book 'Curing the Incurable'. He cites 1,200 journal articles which most doctors practicing today ignore.

The theology of vaccination; that of “pre-emption”, requires a bedrock belief that there is no alternative. Especially no curative alternative.

If your child comes down with a childhood illness, that you could cure safely and effectively while at the same time permitting that child to develop and strengthen their natural immunity…why would you need to vaccinate?

That alternative is Vitamin C.

It’s hidden in plain sight. It’s wrapped within the lie of “dosage”.

It would have been so much harder to build The Church of Vaccination if the knowledge of High Dose Vitamin C was commonplace.

It would have also been so much harder to build the trillion-dollar cancer and chemotherapy industrial complex if people knew that High Dose Vitamin C was effective against cancer.

That email from Amelia set me on a path to learn more from Dr. Thomas Levy who has made it his life’s work to teach people about Vitamin C.

He has plenty of content on YouTube, and I have chosen the below lecture to be the cornerstone of this stack as he covers a lot of ground with great bird’s eye views on many subjects.

It’s here that I learned for the first time about oxidative stress. I had heard the term before but didn’t know what it meant and most certainly didn’t think it had anything to do with “electrons”.

Having been taught by Liam Scheff about The Electric Universe, the penny was ready to drop.

The purpose of this stack is to do for you what Amelia did for me, which is to open the door into the world of Vitamin C so that it can be a powerful tool in your family’s toolkit of looking after your own health and being less dependent on industrial injurious Big Medicine.

So, first let’s spend some time with Dr. Thomas Levy.

I have provided a full summary of the lecture, but it’s definitely worth making the time to listen to the modern Godfather of Vitamin C himself.

Vitamin C and the Mitochondria - Dr Thomas Levy - YouTube

Comprehensive Summary

In this lecture Dr. Thomas Levy discusses the importance of vitamin C and its role in cellular health, specifically relating to mitochondria and energy production.

He begins by stating that vitamin C, mitochondria, and cellular energy metabolism are closely interlinked, centering on the concept of energy production at the cellular level. If cells are producing adequate energy, the body is healthy; if not, illness results. He emphasizes vitamin C's role as the "fuel" that powers cellular metabolism.

Vitamin C Overview

Dr. Levy provides an overview of key properties of vitamin C:

• It is the "king" of antioxidants and plays a central role in redox reactions, donating electrons. Good health requires robust electron flow.

• Its small molecular size and structural similarity to glucose allows ready cellular access.

• It is unusually stable which allows it to persist intracellularly.

• It can donate two electrons, unlike most antioxidants.

• It regenerates oxidized antioxidants like glutathione.

He states vitamin C is not toxic at high doses and rejects the analogy that toxicity occurs from overconsumption as with water intoxication.

Oxidative Stress and Disease

A key concept he stresses is that oxidation of biomolecules directly causes disease. Oxidized biomolecules lose function, causing downstream effects. He proposes that all diseases at root involve oxidation of biomolecules and that all effective therapies involve reduction and repair of these oxidized molecules.

Toxins, pathogens (mainly oral) are major drivers of oxidation. He states that "toxin" and "pro-oxidant" are synonymous. Antioxidants counter the effects of pro-oxidants.

Mitochondria and Energy

He provides an overview of mitochondria, which produce 36 molecules of ATP per glucose molecule via cellular respiration, far more efficient than cytoplasmic glycolysis which yields 2 ATP molecules. Mitochondria constitute about 20% of body weight and are present in all cells except mature red blood cells. They have a half-life of 5-12 days.

He conceptualizes other cellular components as "support structures" for keeping mitochondria healthy. Mitochondria are vulnerable to oxidative damage since they are the sites of electron transport; interventions should aim to reduce cytoplasmic oxidative stress which directly impacts mitochondrial function.

Vitamin C, Mitochondria, and Cell Health

Vitamin C administration increases vitamin C concentrations inside mitochondria. It supports glutathione, a major antioxidant, and other intracellular antioxidants through its recycling effects.

Getting high vitamin C concentrations inside cells is key to efficacy. Liposomal vitamin C accomplishes this efficiently by mimicking extracellular vesicles in biology. This avoids the energy expenditure of transporters required for unencapsulated vitamin C.

Quotes:

• "if you're producing energy in excess of what you absolutely required you're healthy if you're not you're sick and if you're severely depleted you're very sick so in this little presentation I'm going to first start out with some of what I consider to be important foundational concepts"

• "I'll tell you vitamin C is literally not figuratively literally the fuel on which the body runs"

• "all antioxidants can participate in redox reactions to one degree or another what vitamin C is clearly the king of this cascade"

• "so not only do electrons produce energy they also disseminate the energy"

• "when those biomolecules are replete they have their full contingent of electrons they're stable and normal and able to function normally"

• "100 percent of chronic degenerative diseases, cancer, heart disease you name it have increased intracellular oxidative stress"

• "when you have something simplistic and true and that simplistic point is that if you can get high amounts of reduced vitamin C inside the cell you're winning and your patients winning"

Statistics:

• 20% of body weight is mitochondria

• Mitochondria produce 36 molecules of ATP per glucose molecule versus 2 molecules from cytoplasmic glycolysis

• 95%+ of toxins affecting health daily originate from infections, mostly oral

• A CRP level above 1 indicates oxidative stress and need for intervention

• Calcium channel blockers reduce all cause mortality since they make every cell healthier by lowering calcium

• Magnesium, vitamin D3, vitamin C, and vitamin K each independently reduce all cause mortality

While we are here Levy also spends a fair amount of time on Magnesium:

Magnesium is highlighted as probably the most important supplement to take, even more so than vitamin C. Magnesium is an essential cofactor for hundreds or thousands of enzymatic reactions in the body. Additionally, it serves a key role as a physiological regulator of calcium. High magnesium levels lower calcium levels, and vice versa.

Since high intracellular calcium is tied to increased oxidative stress and poorer cell health, magnesium counteracts this by suppressing elevated calcium. In this way, magnesium confers protective effects in the body. No other substance can substitute for magnesium in performing these functions.

Given magnesium's central importance for energy metabolism, detoxification pathways, and calcium homeostasis, Dr. Levy states that if one were to only take a single supplement, magnesium should be it. The wide-ranging benefits of optimizing magnesium intake make it critical. While vitamin C and other antioxidants can partially stand in for each other, magnesium is irreplaceable. Maximizing and maintaining healthy magnesium levels is a top priority.

So, one of the main questions for me coming out of Levy’s lecture was:

What are the role of electrons in oxidative stress?

Oxidative stress occurs when there is an imbalance between the production of free radicals and the ability of the body to counteract their harmful effects through the neutralization by antioxidants. At the core of oxidative stress is the behavior of electrons, specifically in molecules like reactive oxygen species (ROS) and reactive nitrogen species (RNS).

• Free Radicals: A free radical is an atom or molecule that has one or more unpaired electrons in its outer orbit. These unpaired electrons make the molecule highly reactive, as it seeks to either donate or receive an electron to achieve stability. This can result in damage to cellular components like proteins, lipids, and DNA.

• Formation of ROS/RNS: In cellular processes like mitochondrial respiration, the reduction of molecular oxygen can lead to the formation of superoxide anion, a type of ROS. This superoxide can then be converted into other ROS like hydrogen peroxide and hydroxyl radicals. Similarly, nitrogen-based free radicals like nitric oxide can form RNS.

• Chain Reactions: When a free radical steals an electron from a stable molecule, it turns that molecule into a free radical, setting off a chain reaction. This propagation can cause extensive cellular damage.

• Antioxidants: Antioxidants work by donating electrons to free radicals without becoming unstable themselves, effectively neutralizing the free radicals and stopping the chain reaction. Antioxidants can be enzymes produced by the body (e.g., superoxide dismutase, catalase, glutathione peroxidase) or nutrients obtained from the diet (e.g., vitamin C, vitamin E).

• Oxidative Damage: In the absence of adequate antioxidants, or due to the excessive production of ROS/RNS, oxidative stress ensues. This can damage cellular structures and is implicated in aging and various diseases like cancer, cardiovascular diseases, and neurodegenerative disorders.

In summary, the role of electrons in oxidative stress is central, as it's the movement, sharing, or stealing of electrons that defines the reactivity of atoms and molecules in biological systems. This reactivity underlies the formation of free radicals, the propagation of oxidative damage, and the mechanism by which antioxidants neutralize this damage.

Now, let’s look at Levy’s book, Curing the Incurable, via this excellent book review from Jed Stuber from 2015.

Book review: ‘Curing the Incurable: Vitamin C, Infectious Diseases, and Toxins’

According to Dr. Thomas Levy, the idea that the typical doctor stays on top of the latest medical science by reading medical literature is terribly naive. Curing the Incurable: Vitamin C, Infectious Diseases, and Toxins argues there is overwhelming evidence in the medical literature that Vitamin C cures a host of infectious diseases, but modern medicine doesn’t realize it.

A movie called First Do No Harm came out about 15 years ago, and Dr. Levy recalls discussing it with fellow doctors. In the film, a young boy with epileptic seizures is unresponsive to medication, so his mother goes to the library and “discovers” that a high fat ketogenic diet eliminates seizures in a significant percentage of patients. The movie dramatizes the conflict between the mom and doctors. She is ridiculed and threatened with legal action to keep her from trying the diet in an attempt to avoid surgery. The diet works and the movie ends happily. The boy is healthy and the small community that was so divided over his treatment is at peace again.

Dr. Levy’s colleagues in the doctors’ lounge were indignant at the movie and news reports it spawned. The slightest suggestion that there might be something to a ketogenic diet made them angry, even though most of them had never heard of it. Some said the evidence was only “anecdotal” and others said they would need to see a “full bibliography.” Dr. Levy logged into one of the popular databases of medical literature that doctors have access to and in a matter of minutes found 180 references to the ketogenic diet. Any doctor who bothered to look could easily see that it’s been well established as an effective treatment for epilepsy for 75 years. (Visit CharlieFoundation.org.)

Dr. Levy says that most doctors become set in their ways through their medical school textbooks and residency. “Once something gets etched into the pages of the medical textbook, and medical school professors throughout the country teach it to medical students and doctors in post-graduate training, any contradictions to this orthodox body of knowledge get summarily ignored once these impressionable trainees become practicing physicians.”

Dr. Levy speaks from experience. After undergraduate studies at Johns Hopkins, he did his medical degree and residency at Tulane, where he specialized in cardiology. He also received a law degree and is a member of the bar in Colorado and the District of Columbia. He has served on hospital review boards, conducted investigations, published a variety of medical journals, and been a professor at a medical school. Now he lectures all over the world, telling this story: The more he delved into the medical literature about Vitamin C, the more amazed he became.

This background is important for answering a common objection to Dr. Levy’s work on Vitamin C. It sounds too good to be true. If Vitamin C really can cure major diseases, why aren’t more doctors using it?

Curing the Incurable begins with polio, because the evidence for it being cured by Vitamin C is staggering. Studies showing Vitamin C can inactivate polio date back to the 1930s. Then there is the forgotten work of Dr. Frederick Klenner.

“At the height of the polio epidemic in 1949, when all young parents lived in fear that their babies and young children would be the next victims, Frederick R. Klenner, M.D., published that he had successfully cured 60 out of 60 polio patients who had presented in his office or to the emergency room. Furthermore, he reported that none of the 60 patients treated had any residual damage from the polio virus that often left its survivors crippled for life. This evidence was subsequently presented by Klenner in 1949 to an annual session of the American Medical Association that dealt with the treatment of polio patients.”

A small minority of doctors continue to treat polio and other infectious diseases with Vitamin C, and there are impressive studies about Vitamin C that continue to be published in the medical literature right up to the present day.

Dr. Levy argues that there is plenty of evidence to conclude Vitamin C cures, prevents, and reverses a host of infectious diseases. The book cites more than 1,200 scientific references. Where he finds the evidence compelling, but would like to see additional confirming research done, he adds a question mark.

Before getting into all the research, Levy presents some basic concepts and historical perspectives.

There are several entrenched misconceptions about Vitamin C therapy, starting with basic terminology. “Vitamin” is a term scientists use in a precise way to describe substances measured in very small trace amounts, but doctors who successfully treat infectious diseases with Vitamin C use doses 10,000 to 20,000 times the trace amounts. According to Dr. Levy, the ascorbates we call Vitamin C should never have been labelled a Vitamin in the first place. The dosing misconception shows up in the medical literature too. There are some studies claiming to demonstrate Vitamin C’s ineffectiveness in treating various diseases, but they are based on the false premise that using extremely small doses is valid.

Another common misunderstanding is that the very small amount of Vitamin C that prevents scurvy, or the amount in the World War II-era government recommendations known as Recommended Daily Allowance, is enough to maintain optimum health. Trace amounts of Vitamin C do prevent scurvy, but much larger amounts are necessary for the body to maintain healthy and optimum metabolic functions. Furthermore, there is much evidence that Vitamin C depletion is often the reason that many common infectious diseases develop in the first place.

A third misconception is that eating healthy foods can supply the body with optimum amounts of Vitamin C. Here Dr. Levy is asserting something consistent with the Christian doctrine of the Fall. Creation—including our bodies and our food—is subject to decay, and wisdom calls for supplementing our diets.

Dr. Levy recounts the fascinating history, dating back 85 years, of pioneering doctors treating infectious diseases with Vitamin C. They developed very simple protocols. They administered Vitamin C every few hours. The patient’s fever or other symptoms usually improved. If the patient didn’t improve, they gave more Vitamin C more often.

If the three rules of real estate are “location, location, location,” the three rules of optimum Vitamin C are “dose, dose, dose,” Dr. Levy says.

One of the challenges of using larger quantities of Vitamin C is that it sometimes causes bowel problems, but this challenge actually helps doctors determine dosage and learn some important things.

If the patient develops loose stools, the Vitamin C is not being used by the body and it is going into the excretory system. Then the dosage is backed down a bit, and the optimal dose has been determined.

Depending on the disease, how far it has advanced (or how much it has been reversed), and the individual patient, the Vitamin C is used up at varying rates. When dealing with major health problems, patients sometimes are able to use 100 to 200 times as much Vitamin C as a healthy person would before reaching the bowel tolerance. Whether adjusting the dosage up or down, the bowel tolerance helps determine the optimal dose.

Doctors have also learned that administering Vitamin C through injections or IVs avoids the bowel problems and requires less Vitamin C, because it is more easily absorbed and used by the body. Another technological innovation called Liposomes began to be developed in the 1960s. It allows patients to take Vitamin C orally, but without bowel problems.

Liposomes are microscopic spheres, molecules that combine a nutrient such as Vitamin C with a lipid. They are very similar to components of the cell walls in the body, and allow the nutrients to be absorbed very efficiently. Research on liposomes is ongoing, and Dr. Levy presents evidence liposomal Vitamin C is even more effective than that administered by IV.

Scientists are still working out all the mechanisms by which Vitamin C has antioxidant and antimicrobial effects in the body. But how it works doesn’t even matter in one sense. Dr. Levy’s point is simply this: study after study confirms that when Vitamin C is administered in optimal doses, it cures major diseases.

In one chapter Dr. Levy goes beyond infectious diseases. He presents evidence that Vitamin C is the “ultimate antidote” to many toxins: alcohol, barbituates, carbon monoxide, endotoxin, methemoglobinemia, poisonous mushrooms, radiation, strychnine, tetanus, venoms, pesticides, and many more.

Dr. Levy also devotes a chapter to answering some common concerns about safety. Again, he presents study after study. Vitamin C has been shown repeatedly to be safe in high doses and over long periods of time. Dr. Levy refutes the suggestion that Vitamin C might contribute to kidney stones. He explains that there is only one rare genetic disease where there is a known reason not to use Vitamin C therapy—G6PD Deficiency.

The final chapter makes some practical suggestions about Vitamin C. In spite of all the evidence supporting optidose Vitamin C therapy, there are challenges to getting it by any method.

Dr. Levy cautions that anyone treating a major disease with Vitamin C should do so under a doctor’s supervision. Depending on the circumstances, a combination of IV, liposomal, and regular oral Vitamin C should be used. Administering it by IV is pretty straightforward, but hydration of the patient must be closely monitored. Additional concerns come into play if there are kidney problems. Calcium ascorbate must never be used. Unfortunately, doctors that offer any kind of optidose therapy are few and far between.

Dr. Levy does recommend that an average healthy adult should be taking 6,000 to 12,000 mg of regular Vitamin C daily to meet the body’s general metabolic needs. Liposomal Vitamin C is now available to consumers to meet this need as well, but unfortunately, it is currently quite expensive.

The benefits of high dose Vitamin C have been known for a very long time.

Its active suppression has been a long-term project. It hardly got a mention during Covid.

Next is a section from the magnificent Dissolving Illusions where Humphries and Bystrianyk give us some history on Vitamin C.

By 1900 deaths from scurvy were rare and steadily decreased. Simultaneously, death from infectious diseases also drastically declined. This is because immune cells are highly dependent on a component of vitamin C called ascorbic acid.

Today we know that vitamin C is vital to several components of the human immune system, including white blood cells. About 50–70 percent of all white blood cells are neutrophils, the primary immune cell type that utilizes vitamin C. This 2004 study shows that vitamin C is also used by granulocytes, or polymorphonuclear leukocytes (PMNs). PMNs are white blood cells that contain a segmented lobular nucleus; they can be further classified into eosinophil, basophil, or neutrophil.

…the ascorbate [vitamin C] pool in the PMNs is used by the PMNs to destroy the engulfed pathogens, as suggested by our results and also by earlier observations that dietary supplementation with vitamin C augments innate immunity.

Innate immunity is the part of cellular immunity that requires no memory of previous infection.

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A paper published in 1949 by Dr. Fred R. Klenner showed the impressive positive effects of ascorbic acid against a number of diseases. One of the diseases discussed was herpes zoster, also known as shingles. It is a disease that can cause severe pain. Dr. Klenner effectively used large doses of ascorbic acid to treat this condition and described how the pain rapidly disappeared in a number of cases.

In herpes zoster 2000 to 3000 mg. of vitamin C was given every 12 hours, this supplemented by 3000 mg. in fruit juice by mouth every two hours. Eight cases were treated in this series, all of adults. Seven experienced cessation of pain within two hours of the first injection and remained so without the use of any other analgesic medication. Seven of these cases showed drying of the vesicles within 24 hours and were clear of lesions within 72 hours… One of the patients, a man of 65, came to the office doubled up with abdominal pain… He was given 3000 mg. of vitamin C intravenously and directed to return to the office in four to five hours… He returned in four hours completely free of pain. He was given an additional 2000 mg. of vitamin C, and following the schedule given above he recovered completely in three days.

A later paper published in 1953 by Dr. Klenner also showed that vitamin C was effective against measles. He found that, when used in large doses, there was a definite positive response manifested by an increased white blood cell count (unlike bacterial infections, viral infections often drop the white blood count, which can be devastating), a drop in fever, and general all-around improvement of the patient. This rise in white blood cell count indicated a mobilizing of the immune system against the measles virus. Dr. Klenner discussed his first attempts at using vitamin C to treat a child with measles.

In the Spring of 1948 measles was running in epidemic proportions in this section of the country. Our first act, then, was to have our own little daughters play with children known to be in the “contagious phase.” When the syndrome of fever, redness of the eyes and throat, catarrh [inflammation of a mucous membrane], spasmodic bronchial cough, and Koplik spots [measles skin spots] had developed and the children were obviously sick, vitamin C was started. In this experiment it was found that 1000 mg every four hours, by mouth, would modify the attack… When 1000 mg was given every two hours all evidence of the infection cleared in 48 hours… the drug (vitamin C) was given 1000 mg every 2 hours around the clock for four days… These little girls did not develop the measles rash during the above experiment and although exposed many times since still maintain this “immunity.”

Dr. Klenner described several other remarkable cases of recovery using vitamin C. One was a 10-month-old baby with measles. The baby had a fever of 105°F, red eyes and throat, catarrh (mucous inflammation), spasmodic cough, and Koplik spots.

1000 mg of vitamin C was given intramuscularly every four hours. After 12 hours the fever was 97.6°F, the conjunctivitis and red throat had cleared, there was no cough… the baby made an uneventful recovery… Four years have now elapsed and there has been no measles.

Another case was an eight-year-old boy who suffered from poliomyelitis. He had conjunctivitis, a sore throat, a high fever of 104°F, nausea and vomiting, and a headache of such intensity that adult doses of aspirin given by his mother had no effect. During the examination, he either rubbed his neck or held his head between his hands, begging for someone to relieve the pain.

Six hours after commencing therapy the neck pain was gone, the headache completely relieved, he could tolerate the ceiling light, his eyes were dry and the redness was definitely clearing. Nausea and vomiting had disappeared, the fever was down to 100.6°F., and he was sitting up in “a straight position in bed” and in a jovial mood while he drank his glass of lime ade. He was discharged from the hospital after receiving 26 grams of vitamin C in a 48-hour period, clinically well.

A 1952 article published by Dr. McCormick described positive results using vitamin C for a number of infectious conditions.

The writer [Dr. McCormick] has previously reported spectacular results by this method in the treatment of tuberculosis, scarlet fever, pelvic infection, septicemia, etc. Concurrently, by this same method, Klenner has reported dramatic results in the treatment of virus diseases, including poliomyelitis, encephalitis, measles, herpes zoster, virus pneumonia, etc.

Vitamin C’s benefit during infection has much to do with the neutralization of bacterial and viral toxins and with the supply of ascorbic acid to white blood cells. But there is another more direct effect on bacteria. Today, scientists are validating the antimicrobial effect of vitamin C on certain bacterial infections. The effect involves oxidative killing via the Fenton reaction, with vitamin C essentially acting as an antibiotic.

In Escherichia coli, a common mechanism of cell death by bactericidal antibiotics involves the generation of highly reactive hydroxyl radicals via the Fenton reaction. Here we show that vitamin C, a compound known to drive the Fenton reaction, sterilizes cultures of drug-susceptible and drug-resistant Mycobacterium tuberculosis, the causative agent of tuberculosis. The bactericidal activity of vitamin C against M. tuberculosis is dependent on high ferrous ion levels and reactive oxygen species production, and causes a pleiotropic effect affecting several biological processes.

An earlier work in 1937 by Dr. Claus W. Jungleblut showed that injections of natural vitamin C were effective in preventing poliomyelitis paralysis in infected monkeys. In his experiment, he found that six times as many animals escaped paralysis following treatment with natural vitamin C than control animals.

The data presented in this paper, which are based on a number of experimental animals almost thrice as large as previously reported, leave no doubt that the administration of natural vitamin C during the incubation period of experimental poliomyelitis is followed by a definite alteration in the severity of the disease.

Pertussis is another disease that consumes large amounts of vitamin C and is effectively ameliorated with high enough doses. A 1936 pilot study by Otani documents more rapid improvement than expected in the majority of his cases, even though his dosing was far too low to have reached an effective threshold. He only used 50 to 200 mg per injection.

Vermillion published a similar study in 1938.

In this small series of twenty-six cases of whooping cough, cevitamic acid seemed to be strikingly effective in relieving and checking the symptoms in all but two of the cases which apparently received little if any relief. It is our opinion that it should be given further trial in all cases of whooping cough regardless of the age of the patient, or the length of time already elapsed since the original symptoms.

But he also used very low doses of cevitamic (ascorbic acid) acid. In 1937 Ormerod reported in a small study group:

Ascorbic acid has a definite effect in shortening the period of paroxysms from a matter of weeks to a matter of days.

His doses were also very low—150 to 500 mg. Given that pertussis is a toxin-mediated disease, these low doses would not have come close to tissue saturation. Sessa and Meier also reported positively on low- dose vitamin C in pertussis.

There are no randomized controlled trials (RCTs) to demonstrate the effect of high-dose vitamin C on the duration and severity of pertussis. However, there are practices that have been caring for very young infants and children for 30 years using high-dose vitamin C, and they have not lost or damaged one of those children. There are thousands of happy mothers who know that vitamin C saved their children from suffering the feared ravages of pertussis. Vitamin C has no known toxic dose and, when used properly, makes whooping cough far more manageable.

Doctors have used vitamin C effectively in cases of measles, scarlet fever, poliomyelitis, pertussis, opiate withdrawal, coronary artery disease, cancer, life-threatening sepsis, encephalitis, pneumonia, and other conditions.

Unfortunately, their work has been forgotten or actively denied.

I will give the final word to Levy, with some excerpts from his 2001 article.

Dental Toxins, Dental Toxicity, Toxicity, Mercury Fillings, Root Canal, Periodontal Disease, Ascorbic Acid, Vitamin C, TomLevyMD.com - Welcome

TREATMENT ALTERNATIVES

Vitamin C, typically as ascorbic acid or sodium ascorbate, should prove to be highly effective against both of these conditions. I say "should" only because their rareness has prevented any single vitamin C researcher from encountering enough cases to conduct a meaningful study and publish it. However, the likelihood that both of these conditions could be completely cured, even in their advanced stages, is compelling. Consider the following information:

The medical literature has clear documentation that high enough doses of injectable vitamin C are almost always effective in curing any of a number of viral infections still considered today to be incurable. Klenner (1949) completely cured 60 out of 60 cases of infantile polio in North Carolina in the middle of a polio epidemic. Several infants already had neurological involvement, but nevertheless recovered completely. Klenner (1951) was also able to bring about a complete recovery by administering enough vitamin C to one five year-old polio victim who had already been paralyzed in both legs for over four days. Klenner (1949, 1953, 1971, and 1974) also reported the repeated ability to rapidly cure viral diseases such as encephalitis (often presenting in the comatose state), herpes infections, acute hepatitis, measles, and mumps. Klenner found that his only inadequate responses to treatment were overcome by increasing the vitamin C dose and/or going from an oral to an injectable form of vitamin C. Cathcart (1981) also reported an incredible success in the treatment of many viral diseases for which no specific anti-viral agents exist today. Of particular interest, he reported that he never had a case of viral hepatitis fail to respond to intravenous vitamin C. Furthermore, he never observed a single case of acute hepatitis treated appropriately with vitamin C to persist long enough to evolve to the status of chronic hepatitis. Finally, although no specific studies looking at the effects of vitamin C on smallpox could be found, Kligler and Bernkopf (1937) were able to determine that relatively small doses of vitamin C could easily kill the vaccinia virus, which is the virus in the vaccine that induces immunity to smallpox.

Vitamin C has also been documented to rapidly resolve a number of non-viral infectious diseases that do not readily resolve in the absence of vitamin C therapy. Diptheria (Klenner, 1949 and 1971), whooping cough (Otani, 1936 and 1939; Ormerod et al., 1937), and tetanus (Klenner, 1954) all have responded very well to vitamin C. Of great interest as well is that all three of these infections are associated with very significant microbe-generated toxins, much like anthrax. Jungeblut and Zwemer (1935) found that vitamin C both inactivated diphtheria toxin in the test tube and protected guinea pigs against the fatal outcome of being injected with otherwise fatal doses of diphtheria toxin. Dey (1966) showed that enough injected vitamin C would completely protect rats from otherwise fatal doses of tetanus toxin.

Klenner never encountered a virus he could not cure, although he used doses of vitamin C that are considered outrageously high today, even though such doses are nevertheless decidedly non-toxic. His initial dosing of vitamin C would go as high as 700 mg/kg body weight, which could exceed 70 grams for a large man. Furthermore, he would repeat this high dosing in only a few hours if no drop in fever or clear clinical improvement resulted. He never reported any toxicity from vitamin C dosed in this fashion. However, he repeatedly reported that initially unresponsive patients did finally respond when enough vitamin C was administered frequently enough. From the very current scientific literature we know that 60 grams of vitamin C can be repeatedly infused without toxicity over only an 80-minute period. Furthermore, 50-gram intravenous doses of vitamin C can be given daily for 8 weeks without any side effects other than improved health (Casciari et al., 2001).

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Regardless of any skepticism that the reader may have toward such high-dose vitamin C therapy, it is absolutely unthinkable not to try it or add it to whatever protocol is being administered to the patient. At the very least, all acute infectious diseases rapidly metabolize vitamin C, and all acutely ill patients are consequently deficient in vitamin C. The administration of vitamin C should always be undertaken when acute vitamin C deficiency is a certainty, even if one does not believe that enough vitamin C can be a definitive therapy by itself.

This is a great 2009 New Zealand story, back when journalists did a bit of journalism.

VITAMIN C SAVES VENTILATOR PATIENT ON DEATH'S DOOR

Vitamin C Resources

IV Vitamin C Protocols and Procedures | Dr. Thomas Levy, MD, JD, Vitamin C Specialist (tomlevymd.com)

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FREE Book Summary: The Deep Hot Biosphere by Thomas Gold (Abiogenic Oil)

FREE Book Summary: The Peanut Allergy Epidemic by Heather Fraser

FREE eBook: What is a woman? - “We don’t know yet.”

FREE eBook: The Climate™

FREE eBook: A letter to my two adult kids - Vaccines and the free spike protein