Jan 7, 2023ยทedited Jan 7, 2023Liked by Unbekoming
This has a lot of fantastic basic and while my own understanding includes many thousands of hours reading and learning it's still far from a place to critique most of the citations.
However with the case of flu vaccine you are so far from the mark it's an easy correction.
"This is why some vaccines (like the flu vaccine) can provide long-lasting protection against certain diseases."
If flu shots offered durable protection it wouldn't be a yearly jab. Best case based on CDC data the flu vaccines have 14% efficacy & even this seems generous since not everyone gets every flu.
Next like Covid & all coronavirus they're always in the background of our atmosphere it's an aerosolized virus which means primary immune response is mucousal immunity. The flu shot never has interaction with your respiratory system & these fail on fundamentals.
Add to the points of failure that the jabs are chasing mutations that happen withe each and every transmission. It's a wild guess what to manufacture & ship to protect against some yet unknown variant while Mother Nature never rests, lucky us. A healthy immune system recognizes the most stable proteins in the virus & most killed off in the nose and throat.
Big time kudos & thanks for the Herculean effort it's a wonderful resource gift!! :~)
Excellent pickup, thank you. I have relied on an ai assistant in parts, and it can pump out BS "approved" narrative which I generally clean up but missed that one. ๐
I kinda thought that, but gave the benefit of the doubt that it might be a typo. I know sometimes I am typing along, my brain going way faster than my fingers, and I leave out words or add words that change the entire meaning of my sentence. ......Then there's all the regular typos. ๐๐๐
The immune system is complex! There are some important fundamental distinctions on immune cells worth learning more aboutโฆ
Hereโs an opportunity: IPAK-EDU has a learn-at-home course starting this month all about the immune system, how it works, and its impact on disease, including cancer.
I would also add that the identification of the gut as playing a vital role in the immune system (@goddeketal and @SabinehazanMD on twitter, at least one of them has a substack I think) also plays into this idea of man's oneness with the ecosphere (discussed in article and comments) in that we ("individuals") are not a single body but comprise a complex ecosystem which is poorly understood, and probably never will be.
"So, with all that said, I feel highly qualified to talk about cancer, immunity and covid vaccines, as only someone who doesnโt know much about all three can".
And with a damn sight more honesty and integrity than any authorities and most doctors.
Have you come across Brian Mowreyโs substack ? This article is about IgG4 but only in the context of allowing persistent infections, not relating to cancer here. He has a facetious comedy style of writing sometimes with a heavy sense of irony ( as demonstrated by his latest post โ A Cardiologist Explains...) so do persist! He first wrote about the IgG4 paper 5 months ago when it was in pre-print. He is very analytical and often has a slightly different nuance on all the topics discussed in the substacks.
"Epoptosis is a type of economic death that occurs during the abnormal development and functioning of an organisation. It is a highly regulated process that involves the deactivation of specific businesses that cause the economy to undergo structural changes and be dismantled in a controlled manner."
Important topic. The Immune System 101 is good in some respects, but glosses over important aspects. I recognize the intent is to make it simple, but thereโs simplifying, and then there is over-simplification. Just my 2 cents.
That's the reason for the Varela essay, to make the point that the simplification inherent in 101 is an oversimplification that renders it wrong. So, I agree with you.
Jan 7, 2023ยทedited Jan 7, 2023Liked by Unbekoming
Hmm, thatโs a bit unconvincing for me. Iโm not speaking of an alternative view on the immune system. The 7 point list highlighted at the outset omits too much and doesnโt do adequate justice to the truly incredible biology of the immune system.
I could not access the Varela essay in full, so perhaps that would change my read. And not saying the quoted bits from Valera are incongruent either.
The link to the pdf is working at my end, unfortunately I cannot directly upload it. But I think you will find that it makes your point precisely and elegantly.
I would like to learn more about the immune system. I'm specifically curious about what evolutionary biology has to say as to who the various layers of it evolved. Additionally, if the layers evolved separately at all then how did the integration of them go? How much can what happens in the cardiovascular system effect what happens in the mucousal layer and vice verca?
While I want to learn more I don't have a set plan on how to go about it. So I guess I'll stick with substack immunology osmosis for now
Too much dissection of a lot of speculative science. Ditto for mechanistic arguments. No one knows for sure. These are suitable for rabbinical debates not medicine. The only thing that counts in clinical medicine is empiricism. Proper studies and case reports. Unfortunately the studies are ALL ruined by financial interests. This sort of thing is all we have that is meaningful, and there is FAR more of it: "Even before the boosters were rolled out to the public, the Vaccine Adverse Events Reporting System (VAERS) of the Dept of Health and Human Services (HHS) showed vastly more cancers following COVID vaccines than for all other vaccines during the 30-year history of VAERS. These new cancers following the COVID vaccines accounted for 97.3% of cancers reported.
Some musings on what is going on in the world of man and its' effects on Gaia. After all our effects on Earth are causing Earth an immunological response.
Divided and Conquer.
From the book I am re-reading for about the 3rd time in about 15 years "Microcosmos" by Lynn Margulis and Dorian Sagan, I am learning that life through meiotic sex is very expensive and thus there must be something else going on. Thinking about it again I have a few words to articulate my non verbal perception of the chapter on SEX in that book.
I agree . I think that Plant and Animal sex is so expensive because we are a controlled experiment by Gaia. If we could share chromosomes or DNA like our bacterial parents, we would be out of control and may even have destroyed ourselves already. So that is one part of the Divided.
The other is; Dr. Lynn Margulis warns against war against our parents the bacteria, which she calls the Microcosmos. Such a war we cannot win. I suggest that a very small portion of mankind declared war with the invention of herbicides and pesticides perhaps even before with the industrial revolution. Perhaps those early warriors against the parents of the bioshpere were ignorant and should be forgiven. But when glyphosate/Roundup entered the picture, there was no longer any doubt in the microcosmos that war had been declared by a very select powerful and hard to see (we can't see them) group of humans that had such intentions by which to direct what they are doing.
Now the war is on. It is why the human side of this war are in a hurry to win at all costs. Why they care little for the destruction caused to all of life, or microcosmos.
Jan 7, 2023ยทedited Jan 7, 2023Liked by Unbekoming
Like you I don't know, my ego is quite retarded in this area. So I call on those who examined this realm with humility and respect to inform. First:
>What I am going to do, is write about what Iโve read and learnt, ...who like me doesnโt know anything about all this, to achieve a survival level understanding of the subject.
Reply:
Ah but you do know as does all living. You just don't know with your ego. Pharma and anyone who applies embryonic knowledge from biophysics is worse than little children playing with a loaded gun. These people are out of their depths and reckless to say the least.
I feel the idea of Gaia is most helpful in developing equanimity toward all humans. But most important to see humans as not so important. We need to have perspective to evolve with Earth/Gaia as she works with the situation humans have created.
The Revenge of Gaia
Copyright ยฉ 2006 by James Lovelock
A CIP catalog record for this book is available from
the Library of Congress
eISBN : 978-0-465-00866-7
excerpt from the forward by CRISPIN TICKELL
The main difference between the past and today is that our problems are truly global. As Lovelock points out, we are currently trapped in a vicious circle of positive feedback. What happens in one place very soon affects what happens in others. We are dangerously ignorant of our own ignorance, and rarely try to see things as a whole. If we are eventually to achieve a human society in harmony with nature, we must be guided by more respect for it. No wonder that some have wanted to make a religion of Gaia, or of life as such. This book is a marvellous introduction to the science of how our species should make its peace with the rest of the world in which we live.
and
Lynn Margulis - Slanted Truths
page 70 - 73
Thus, at the amoeba level of biological organization, "self' inside the same cell-indeed, inside the same vacuole of the same cell-can already clearly be distinguished from "food." Inspection of the
microbiological literature shows, in fact, "sense-of-self' awareness is already present in the virus-infected bacterial world.
***
There is much more to this. But if the self of the bacteria and the self of our immune system can distinguish other, then the way we sense other living selves with our ego senses is crude indeed.
I think one take away from all this, is that they know what they have done, but rather than explain it through a "depopulation" lens, I think it's better understood through a "they don't care" lens.
This has a lot of fantastic basic and while my own understanding includes many thousands of hours reading and learning it's still far from a place to critique most of the citations.
However with the case of flu vaccine you are so far from the mark it's an easy correction.
"This is why some vaccines (like the flu vaccine) can provide long-lasting protection against certain diseases."
If flu shots offered durable protection it wouldn't be a yearly jab. Best case based on CDC data the flu vaccines have 14% efficacy & even this seems generous since not everyone gets every flu.
Next like Covid & all coronavirus they're always in the background of our atmosphere it's an aerosolized virus which means primary immune response is mucousal immunity. The flu shot never has interaction with your respiratory system & these fail on fundamentals.
Add to the points of failure that the jabs are chasing mutations that happen withe each and every transmission. It's a wild guess what to manufacture & ship to protect against some yet unknown variant while Mother Nature never rests, lucky us. A healthy immune system recognizes the most stable proteins in the virus & most killed off in the nose and throat.
Big time kudos & thanks for the Herculean effort it's a wonderful resource gift!! :~)
Excellent pickup, thank you. I have relied on an ai assistant in parts, and it can pump out BS "approved" narrative which I generally clean up but missed that one. ๐
Always my pleasure knowledge is power that multiplies when we pass it on, lucky us!
Thank you! I saw that and it almost made me stop reading expecting further BS
I kinda thought that, but gave the benefit of the doubt that it might be a typo. I know sometimes I am typing along, my brain going way faster than my fingers, and I leave out words or add words that change the entire meaning of my sentence. ......Then there's all the regular typos. ๐๐๐
The immune system is complex! There are some important fundamental distinctions on immune cells worth learning more aboutโฆ
Hereโs an opportunity: IPAK-EDU has a learn-at-home course starting this month all about the immune system, how it works, and its impact on disease, including cancer.
THE BIOLOGY OF THE IMMUNE SYSTEM
w/ James Lyons-Weiler
Direct Registration Link: https://ipak-edu.org/registration/?store-page=The-Biology-of-the-Immune-System-p412473268
Excellent, thanks.
Register with referrer code: JUSTFACTS
Knowledge is Power!
Thank you!
I would also add that the identification of the gut as playing a vital role in the immune system (@goddeketal and @SabinehazanMD on twitter, at least one of them has a substack I think) also plays into this idea of man's oneness with the ecosphere (discussed in article and comments) in that we ("individuals") are not a single body but comprise a complex ecosystem which is poorly understood, and probably never will be.
"So, with all that said, I feel highly qualified to talk about cancer, immunity and covid vaccines, as only someone who doesnโt know much about all three can".
And with a damn sight more honesty and integrity than any authorities and most doctors.
https://unglossed.substack.com/p/tolerance-maims-and-kills-potential
Have you come across Brian Mowreyโs substack ? This article is about IgG4 but only in the context of allowing persistent infections, not relating to cancer here. He has a facetious comedy style of writing sometimes with a heavy sense of irony ( as demonstrated by his latest post โ A Cardiologist Explains...) so do persist! He first wrote about the IgG4 paper 5 months ago when it was in pre-print. He is very analytical and often has a slightly different nuance on all the topics discussed in the substacks.
I have but hadnโt seen that one, thanks ๐
"Epoptosis is a type of economic death that occurs during the abnormal development and functioning of an organisation. It is a highly regulated process that involves the deactivation of specific businesses that cause the economy to undergo structural changes and be dismantled in a controlled manner."
Very few word changes required.
๐ฏ๐๐ป
Important topic. The Immune System 101 is good in some respects, but glosses over important aspects. I recognize the intent is to make it simple, but thereโs simplifying, and then there is over-simplification. Just my 2 cents.
That's the reason for the Varela essay, to make the point that the simplification inherent in 101 is an oversimplification that renders it wrong. So, I agree with you.
Hmm, thatโs a bit unconvincing for me. Iโm not speaking of an alternative view on the immune system. The 7 point list highlighted at the outset omits too much and doesnโt do adequate justice to the truly incredible biology of the immune system.
I could not access the Varela essay in full, so perhaps that would change my read. And not saying the quoted bits from Valera are incongruent either.
The link to the pdf is working at my end, unfortunately I cannot directly upload it. But I think you will find that it makes your point precisely and elegantly.
If you email me at unbekoming@outlook.com I will send it to you directly.
https://onedrive.live.com/?authkey=%21ALAMBGmuEiaHQRg&cid=A1506D9F8F256650&id=A1506D9F8F256650%21119730&parId=A1506D9F8F256650%21110117&o=OneUp
I would like to learn more about the immune system. I'm specifically curious about what evolutionary biology has to say as to who the various layers of it evolved. Additionally, if the layers evolved separately at all then how did the integration of them go? How much can what happens in the cardiovascular system effect what happens in the mucousal layer and vice verca?
While I want to learn more I don't have a set plan on how to go about it. So I guess I'll stick with substack immunology osmosis for now
Too much dissection of a lot of speculative science. Ditto for mechanistic arguments. No one knows for sure. These are suitable for rabbinical debates not medicine. The only thing that counts in clinical medicine is empiricism. Proper studies and case reports. Unfortunately the studies are ALL ruined by financial interests. This sort of thing is all we have that is meaningful, and there is FAR more of it: "Even before the boosters were rolled out to the public, the Vaccine Adverse Events Reporting System (VAERS) of the Dept of Health and Human Services (HHS) showed vastly more cancers following COVID vaccines than for all other vaccines during the 30-year history of VAERS. These new cancers following the COVID vaccines accounted for 97.3% of cancers reported.
As a former oncologist and tumor immunologist, you did quite well. Bravo. ๐๐ป๐๐ป๐๐ป๐๐ป
Excellent, thank you!!
Some musings on what is going on in the world of man and its' effects on Gaia. After all our effects on Earth are causing Earth an immunological response.
Divided and Conquer.
From the book I am re-reading for about the 3rd time in about 15 years "Microcosmos" by Lynn Margulis and Dorian Sagan, I am learning that life through meiotic sex is very expensive and thus there must be something else going on. Thinking about it again I have a few words to articulate my non verbal perception of the chapter on SEX in that book.
I agree . I think that Plant and Animal sex is so expensive because we are a controlled experiment by Gaia. If we could share chromosomes or DNA like our bacterial parents, we would be out of control and may even have destroyed ourselves already. So that is one part of the Divided.
The other is; Dr. Lynn Margulis warns against war against our parents the bacteria, which she calls the Microcosmos. Such a war we cannot win. I suggest that a very small portion of mankind declared war with the invention of herbicides and pesticides perhaps even before with the industrial revolution. Perhaps those early warriors against the parents of the bioshpere were ignorant and should be forgiven. But when glyphosate/Roundup entered the picture, there was no longer any doubt in the microcosmos that war had been declared by a very select powerful and hard to see (we can't see them) group of humans that had such intentions by which to direct what they are doing.
Now the war is on. It is why the human side of this war are in a hurry to win at all costs. Why they care little for the destruction caused to all of life, or microcosmos.
Like you I don't know, my ego is quite retarded in this area. So I call on those who examined this realm with humility and respect to inform. First:
>What I am going to do, is write about what Iโve read and learnt, ...who like me doesnโt know anything about all this, to achieve a survival level understanding of the subject.
Reply:
Ah but you do know as does all living. You just don't know with your ego. Pharma and anyone who applies embryonic knowledge from biophysics is worse than little children playing with a loaded gun. These people are out of their depths and reckless to say the least.
I feel the idea of Gaia is most helpful in developing equanimity toward all humans. But most important to see humans as not so important. We need to have perspective to evolve with Earth/Gaia as she works with the situation humans have created.
The Revenge of Gaia
Copyright ยฉ 2006 by James Lovelock
A CIP catalog record for this book is available from
the Library of Congress
eISBN : 978-0-465-00866-7
excerpt from the forward by CRISPIN TICKELL
The main difference between the past and today is that our problems are truly global. As Lovelock points out, we are currently trapped in a vicious circle of positive feedback. What happens in one place very soon affects what happens in others. We are dangerously ignorant of our own ignorance, and rarely try to see things as a whole. If we are eventually to achieve a human society in harmony with nature, we must be guided by more respect for it. No wonder that some have wanted to make a religion of Gaia, or of life as such. This book is a marvellous introduction to the science of how our species should make its peace with the rest of the world in which we live.
and
Lynn Margulis - Slanted Truths
page 70 - 73
Thus, at the amoeba level of biological organization, "self' inside the same cell-indeed, inside the same vacuole of the same cell-can already clearly be distinguished from "food." Inspection of the
microbiological literature shows, in fact, "sense-of-self' awareness is already present in the virus-infected bacterial world.
***
There is much more to this. But if the self of the bacteria and the self of our immune system can distinguish other, then the way we sense other living selves with our ego senses is crude indeed.
That was great! Thank you.
Perfectly thought and said.
Yeeees! Yes and, Yes what if... Excellent, thank you, makes a lot of sense
to me!
I think one take away from all this, is that they know what they have done, but rather than explain it through a "depopulation" lens, I think it's better understood through a "they don't care" lens.